Dice the Roma tomatoes and onions. Finely chop the cilantro and mince the garlic. Place the tomatoes, onions, and garlic in a bowl. Add salt, pepper, the juice of 2 limes, and finely chopped cilantro. Gently toss everything together until well mixed.
Place the tilapia fillets on a large plate and drizzle with olive oil. In a small bowl, mix the paprika, garlic powder, onion powder, salt, and pepper. Sprinkle seasoning evenly over the fillets.